Pistol-Use this gun for a long range target and also to shoot those flying enemy.
Shotgun-Use this in close range, the closer, the better. It contains heavy blast into the enemy so enjoy.
Ripper-It fires off very fast and is good to get those monsters away if you have 10 of them coming at you! Just watch your ammo.
RPG-This baby will blast you and your baby mamas away. Just aim a little down so the blast will have a better chance hitting your enemy.
Pipe Bombs-These are pretty cool to mix with some tripbombs, better explode for you bang. Hit (default 6) to throw more pipe bombs.
Shrinker-Turns your enemy into a small guy so you can kill him with dukes mighty foot. Hint: Crouch down to get a better view where he is and if your small keep turning 90 degrees before he gets to you, it will take time to get it.
Devastator-Staraight out of the Pentagon's top secret labs comes this double barreled brute of a weapon which lets loose swarms of miniature stinger missles in the direction of your enemies.
Tripbomb-After a 2 second delay you better be out of its way because it will activate and waits until a enemy "trips" over the red beam it emitts. Add some pipe bombs to make the effect more bloody. Place them in narrow areas or under the water.
Freezer-This weapon will frezze your enemy so you can go up and kick him with dukes might foot. If you want you can also shoot it and remember to collect his atomic health he so kindly gave to you.